Search results for "Adapter molecule crk"

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Identification of an LPS-Induced Chemo-Attractive Peptide from Ciona robusta

2020

Background: Previously published work has demonstrated that the LPS injection of Ciona robusta leads to the overexpression of a truncated form of an immune-related mRNA (C8short) by means of Ciona robusta (CR) alternative polyadenylation (APA) (CR-APA). Methods: The 3D structure of the C8short-derived Ciona robusta chemo-attractive peptide (CrCP) was evaluated by homology modeling. The biological activity of the CrCP was studied in vitro using a primary human dermal cell line (HuDe). Real-Time PCR was used to investigate the expression levels of genes involved in cell motility. NF-&kappa

In silicoPharmaceutical ScienceMotilitychemoattractive peptide03 medical and health sciencesAdapter molecule crk0302 clinical medicineWestern blotDrug DiscoverymedicineNF-kBCiona robustaPharmacology Toxicology and Pharmaceutics (miscellaneous)<i>Ciona robusta</i>lcsh:QH301-705.5030304 developmental biology0303 health sciencesmedicine.diagnostic_testChemistryfungiIn vitro3D modellingCell biologyBlotlcsh:Biology (General)Cell cultureinflammation030220 oncology & carcinogenesisSignal transductionCiona robusta; inflammation; chemoattractive peptide; NF-kB; 3D modellingMarine Drugs
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